CD109

Also known as CPAMD7, p180, r150, CD109 molecule

CD109 (Cluster of Differentiation 109) is a human gene.

Gene data

CD109

Name: CD109 molecule
Type: protein-coding
Aliases: CPAMD7, HPA-15, p180, r150

This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014].

via MyGene.info

Gene · Ensembl

CD109 molecule

Symbol: CD109
Biotype: Protein coding
Organism: Homo sapiens
Location: 6:73,695,779-73,828,316
Strand: Forward (+)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

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HomoloGene ID: 25183
genomic start: 74405508
exact match: identifiers.org/ncbigene/135228
genomic end: 74538040
cytogenetic location: 6q13

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CD109 (Cluster of Differentiation 109) is a human gene.

CD109 is a GPI-linked cell surface antigen expressed by CD34+ acute myeloid leukemia cell lines, T-cell lines, activated T lymphoblasts, endothelial cells, and activated platelets (Lin et al., 2002). In addition, the platelet-specific Gov antigen system (HPA15), implicated in refractoriness to platelet transfusion, neonatal alloimmune thrombocytopenia, and posttransfusion purpura, is carried by CD109 (Kelton et al., 1990; Lin et al., 2002).[supplied by OMIM]