CELSR1

Name

cadherin EGF LAG seven-pass G-type receptor 1

Type

protein-coding

Aliases

ADGRC1, CDHF9, FMI2, HFMI2, LMPHM9, ME2, YNS

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

cadherin EGF LAG seven-pass G-type receptor 1

Symbol

CELSR1

Biotype

Protein coding

Organism

Homo sapiens

Location

22:46,360,834-46,537,638

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

via Wikidata · CC0