DIDO1

Also known as BYE1, C20orf158, DATF-1, DATF1, DIDO2, DIDO3, DIO-1, DIO1

Death-inducer obliterator 1 is a protein that in humans is encoded by the DIDO1 gene.

In the Vinony graph

Vinony's link graph records 811 inbound references to DIDO1, and connects out to PubMed, human chromosome 20 and Ensembl genome database project.

It is catalogued under topics including Genes on human chromosome 20 and Transcription factors.

Vinony links it to 6 Wikipedia language editions.

Gene data

DIDO1

Name: death inducer-obliterator 1
Type: protein-coding
Position: 62,877,738–62,937,992 (−)
Aliases: BYE1, C20orf158, DATF-1, DATF1, DIDO2, DIDO3, DIO-1, DIO1, dJ885L7.8
Ensembl: ENSG00000101191
RefSeq RNA: NM_001193369.2, NM_001193370.2, NM_022105.5, NM_033081.3, NM_080796.4
RefSeq protein: NP_001180298.1, NP_001180299.1, NP_071388.2, NP_149072.2, NP_542986.1

Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms. [provided by RefSeq, Jul 2008].