EIF2D
Sign in to saveAlso known as HCA56, LGTN, eukaryotic translation initiation factor 2D
Ligatin, otherwise known as eIF2D, is a protein that in humans is encoded by the LGTN gene. This protein is not a component of the heterotrimeric eIF2 complex, but instead functions in different pathways of eukaryotic translation.
In the Vinony graph
Vinony's link graph records 207 inbound references to EIF2D, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 5 Wikipedia language editions.
Gene data
EIF2D- Name
- eukaryotic translation initiation factor 2D
- Type
- protein-coding
- Position
- 206,571,292–206,612,556 (−)
- Aliases
- HCA56, LGTN
- Ensembl
- ENSG00000143486
- RefSeq RNA
- NM_001201478.2, NM_006893.3, XM_005277509.4, XM_006711196.4, XM_011509257.3
- RefSeq protein
- NP_001188407.1, NP_008824.2, XP_005277566.1, XP_006711259.1, XP_011507559.1
This gene encodes a translation initiation factor involved in the recruitment and delivery of aminoacyl-tRNAs to the P-site of the eukaryotic ribosome in a GTP-independent manner. This gene was previously referred to as ligatin, but is now known to localize to the cytoplasm and localize and function with translation factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 2D
- Symbol
- EIF2D
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:206,571,292-206,612,556
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 38244
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1939
- genomic start
- 206744620
- chromosome
- human chromosome 1
- genomic end
- 206612465
- cytogenetic location
- 1q32.1
- expressed in
- canal of the cervix
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- See also
- References
- Further reading
Ligatin, otherwise known as eIF2D, is a protein that in humans is encoded by the LGTN gene. This protein is not a component of the heterotrimeric eIF2 complex, but instead functions in different pathways of eukaryotic translation.
== Function ==
Excerpted from Wikipedia’s “EIF2D” article, available under the CC BY-SA 4.0 licence.