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GeneQ18053795· pop 5· linked from 354 articles

Also known as ALGV3072, EPG, PRO9904, epithelial mitogen

Epigen also known as epithelial mitogen is a protein that in humans is encoded by the EPGN gene.

Gene data

EPGN
Name
epithelial mitogen
Type
protein-coding
Aliases
ALGV3072, EPG, PRO9904

The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].

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Gene · Ensembl

epithelial mitogen

Symbol
EPGN
Biotype
Protein coding
Organism
Homo sapiens
Location
4:74,308,464-74,317,297
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
19527
genomic end
74316789
genomic start
74308470
cytogenetic location
4q13.3
Sources (3)

via Wikidata · CC0

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Article

3 sections
Contents
  • Function
  • References
  • External links

Epigen also known as epithelial mitogen is a protein that in humans is encoded by the EPGN gene.

== Function == The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate.

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