HSF4
Sign in to saveAlso known as CTM, CTRCT5, heat shock transcription factor 4
Heat shock factor protein 4 is a protein that in humans is encoded by the HSF4 gene.
In the Vinony graph
Vinony's link graph records 815 inbound references to HSF4, and connects out to PubMed, human chromosome 16 and homeobox.
It is catalogued under topics including Genes on human chromosome 16 and Transcription factors.
Vinony links it to 6 Wikipedia language editions.
Gene data
HSF4- Name
- heat shock transcription factor 4
- Type
- protein-coding
- Position
- 67,164,681–67,169,945 (+)
- Aliases
- CTM, CTRCT5
- Ensembl
- ENSG00000102878
- RefSeq RNA
- NM_001040667.3, NM_001374674.1, NM_001374675.1, NM_001538.4
- RefSeq protein
- NP_001035757.1, NP_001361603.1, NP_001361604.1, NP_001529.2
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
heat shock transcription factor 4
- Symbol
- HSF4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:67,164,681-67,169,945
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 100128
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3299
- genomic end
- 67203848
- genomic start
- 67197288
- chromosome
- human chromosome 16
- cytogenetic location
- 16q22.1
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- See also
- References
- Further reading
- External links
Heat shock factor protein 4 is a protein that in humans is encoded by the HSF4 gene.
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
Excerpted from Wikipedia’s “HSF4” article, available under the CC BY-SA 4.0 licence.