KDM5D
Sign in to saveAlso known as HY, HYA, JARID1D, SMCY, lysine demethylase 5D
Lysine-specific demethylase 5D is an enzyme that in humans is encoded by the KDM5D gene. KDM5D belongs to the alpha-ketoglutarate-dependent hydroxylases superfamily.
In the Vinony graph
Within Vinony's link graph, KDM5D is referenced by 816 other articles, and connects out to PubMed, Ensembl genome database project and homeobox.
Vinony files it under EC 1.14.11, Genes on human chromosome Y and Human 2OG oxygenases.
Its subject is documented across 6 Wikipedia language editions.
Gene data
KDM5D- Name
- lysine demethylase 5D
- Type
- protein-coding
- Chromosome
- Y
- Position
- 19,702,298–19,745,148 (−)
- Aliases
- HY, HYA, JARID1D, SMCY
- Ensembl
- ENSG00000012817
- RefSeq RNA
- NM_001146705.2, NM_001146706.2, NM_004653.5, XM_005262560.4, XM_005262561.4
- RefSeq protein
- NP_001140177.1, NP_001140178.1, NP_004644.2, XP_005262617.1, XP_005262618.1
This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
lysine demethylase 5D
- Symbol
- KDM5D
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr Y:19,702,298-19,745,148
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein KDM5D PDB 2E6R.png
Show 8 more facts
- HomoloGene ID
- 55838
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8284
- chromosome
- human Y chromosome
- genomic end
- 21906825
- genomic start
- 21865751
- cytogenetic location
- Yq11.223
- expressed in
- Brodmann area 9
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Lysine-specific demethylase 5D is an enzyme that in humans is encoded by the KDM5D gene. KDM5D belongs to the alpha-ketoglutarate-dependent hydroxylases superfamily.
This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient.
Excerpted from Wikipedia’s “KDM5D” article, available under the CC BY-SA 4.0 licence.