Also known as MXB, MX dynamin like GTPase 2
Interferon-induced GTP-binding protein Mx2 is a protein that in humans is encoded by the MX2 gene.
Gene data
MX2- Name
- MX dynamin like GTPase 2
- Type
- protein-coding
- Aliases
- MXB
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
MX dynamin like GTPase 2
- Symbol
- MX2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 21:41,361,957-41,409,420
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 74299
- exact match
- identifiers.org/ncbigene/4600
- genomic end
- 41409393
- genomic start
- 41361999
- cytogenetic location
- 21q22.3
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Antiviral activity
- References
- Further reading
Interferon-induced GTP-binding protein Mx2 is a protein that in humans is encoded by the MX2 gene.
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon.