P2RY11

Also known as P2Y11, purinergic receptor P2Y11

P2Y purinoceptor 11 is a protein that in humans is encoded by the P2RY11 gene.

In the Vinony graph

Within Vinony's link graph, P2RY11 is referenced by 486 other articles, and connects out to adenosine receptor, PubMed and Ensembl genome database project.

It sits within the topics Genes on human chromosome 19 and G protein-coupled receptors.

Its subject is documented across 7 Wikipedia language editions.

Gene data

P2RY11

Name: purinergic receptor P2Y11
Type: protein-coding
Position: 10,111,689–10,118,085 (+)
Aliases: P2Y11
Ensembl: ENSG00000244165
RefSeq RNA: NM_002566.5
RefSeq protein: NP_002557.2

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product. [provided by RefSeq, Jul 2008].

Pathways

Neuroactive ligand-receptor interaction - Homo sapiens (human)Signal Transduction Signaling by GPCR Class A/1 (Rhodopsin-like receptors)GPCR downstream signalling G alpha (q) signalling events P2Y receptors Nucleotide-like (purinergic) receptors G alpha (s) signalling events GPCR ligand binding

via MyGene.info

Gene · Ensembl

purinergic receptor P2Y11

Symbol: P2RY11
Biotype: Protein coding
Organism: Homo sapiens
Location: 19:10,111,689-10,118,085
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 130446
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/5032
genomic end: 10226048
genomic start: 10111693
chromosome: human chromosome 19
cytogenetic location: 19p13.2
genetic association: narcolepsy

Sources (3)

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Encyclopedic overview

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Contents

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P2Y purinoceptor 11 is a protein that in humans is encoded by the P2RY11 gene.

The product of this gene, P2Y11, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occurring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.

Excerpted from Wikipedia’s “P2RY11” article, available under the CC BY-SA 4.0 licence.