PMP2

Also known as FABP8, M-FABP, MP2, P2, peripheral myelin protein 2, Myelin P2 protein, CMT1G

protein-coding gene in the species Homo sapiens

Gene data

PMP2

Name: peripheral myelin protein 2
Type: protein-coding
Position: 81,440,326–81,447,518 (−)
Aliases: CMT1G, FABP8, M-FABP, MP2, P2
Ensembl: ENSG00000147588
RefSeq RNA: NM_001348381.2, NM_002677.5
RefSeq protein: NP_001335310.1, NP_002668.1

The protein encoded by this gene localizes to myelin sheaths of the peripheral nervous system. The encoded protein can bind both the membrane layers of the sheaths and monomeric lipids, and is thought to provide stability to the sheath. A defect in this gene was shown to be a cause of dominant demyelinating CMT neuropathy. [provided by RefSeq, Jan 2017].