PMP2
Sign in to saveAlso known as FABP8, M-FABP, MP2, P2, peripheral myelin protein 2, Myelin P2 protein, CMT1G
protein-coding gene in the species Homo sapiens
In the Vinony graph
Within Vinony's link graph, PMP2 is referenced by 72 other articles, and connects out to PubMed, human chromosome 8 and Ensembl genome database project.
Vinony files it under Genes on human chromosome 8 and Lipocalins.
Its subject is documented across 8 Wikipedia language editions.
Gene data
PMP2- Name
- peripheral myelin protein 2
- Type
- protein-coding
- Position
- 81,440,326–81,447,518 (−)
- Aliases
- CMT1G, FABP8, M-FABP, MP2, P2
- Ensembl
- ENSG00000147588
- RefSeq RNA
- NM_001348381.2, NM_002677.5
- RefSeq protein
- NP_001335310.1, NP_002668.1
The protein encoded by this gene localizes to myelin sheaths of the peripheral nervous system. The encoded protein can bind both the membrane layers of the sheaths and monomeric lipids, and is thought to provide stability to the sheath. A defect in this gene was shown to be a cause of dominant demyelinating CMT neuropathy. [provided by RefSeq, Jan 2017].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
peripheral myelin protein 2
- Symbol
- PMP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:81,440,326-81,447,518
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PMP2 PDB 1pmp.png
Show 7 more facts
- HomoloGene ID
- 20589
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5375
- genomic end
- 81447439
- genomic start
- 82352561
- chromosome
- human chromosome 8
- cytogenetic location
- 8q21.13
Sources (4)
via Wikidata · CC0