ABL2

Name

ABL proto-oncogene 2, non-receptor tyrosine kinase

Type

protein-coding

Position

179,099,330–179,229,684 (−)

Aliases

ABLL, ARG

Ensembl

ENSG00000143322

RefSeq RNA

NM_001136000.3, NM_001136001.2, NM_001168236.2, NM_001168237.2, NM_001168238.2

RefSeq protein

NP_001129472.1, NP_001129473.1, NP_001161708.1, NP_001161709.1, NP_001161710.1

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009].

via MyGene.info

Gene · Ensembl

ABL proto-oncogene 2, non-receptor tyrosine kinase

Symbol

ABL2

Biotype

Protein coding

Organism

Homo sapiens

Location

1:179,099,330-179,229,684

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein ABL2 PDB 1ab2.png

via Wikidata · CC0