ADGRG6
Sign in to saveAlso known as APG1, DREG, PS1TP2, VIGR, GPR126, LCCS9, adhesion G protein-coupled receptor G6, PR126
G protein-coupled receptor 126 also known as VIGR and DREG is a protein encoded by the ADGRG6 gene. GPR126 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
In the Vinony graph
Vinony's link graph records 486 inbound references to ADGRG6, and connects out to PubMed, Ensembl genome database project and protein.
It sits within the topics Genes on human chromosome 6 and G protein-coupled receptors.
Vinony links it to 6 Wikipedia language editions.
Gene data
ADGRG6- Name
- adhesion G protein-coupled receptor G6
- Type
- protein-coding
- Position
- 142,301,502–142,447,264 (+)
- Aliases
- APG1, DREG, GPR126, LCCS9, PR126, PS1TP2, VIGR
- Ensembl
- ENSG00000112414
- RefSeq RNA
- NM_001032394.3, NM_001032395.3, NM_020455.6, NM_198569.3, XM_005267061.4
- RefSeq protein
- NP_001027566.2, NP_001027567.2, NP_065188.5, NP_940971.2, XP_005267118.1
This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
adhesion G protein-coupled receptor G6
- Symbol
- ADGRG6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:142,301,502-142,447,264
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 10724
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/57211
- genomic end
- 142767403
- genomic start
- 142622991
- chromosome
- human chromosome 6
- cytogenetic location
- 6q24.2
- expressed in
- duodenum
Sources (4)
via Wikidata · CC0
~3 min read
Encyclopedic overview
6 sectionsContents
- Ligand
- Signaling
- Function
- Disease
- References
- External links
G protein-coupled receptor 126 also known as VIGR and DREG is a protein encoded by the ADGRG6 gene. GPR126 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
GPR126 is all widely expressed on stromal cells. The N-terminal fragment of GPR126 contains C1r-C1s, Uegf and Bmp1 (CUB), and PTX-like modules.
Excerpted from Wikipedia’s “ADGRG6” article, available under the CC BY-SA 4.0 licence.
Available in 6 languages
via Wikidata sitelinks · CC0