CD151

Also known as GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24, CD151 molecule (Raph blood group), EBS7

CD151 molecule (Raph blood group), also known as CD151 (Cluster of Differentiation 151), is a human gene.

Gene data

CD151

Name: CD151 molecule (Raph blood group)
Type: protein-coding
Position: 832,705–839,831 (+)
Aliases: EBS7, GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24
Ensembl: ENSG00000177697
RefSeq RNA: NM_001039490.2, NM_004357.5, NM_139029.2, NM_139030.4, XM_024448780.2
RefSeq protein: NP_001034579.1, NP_004348.2, NP_620598.1, NP_620599.1, XP_024304548.1

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008].