CD151

Also known as GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24, CD151 molecule (Raph blood group), EBS7

CD151 molecule (Raph blood group), also known as CD151 (Cluster of Differentiation 151), is a human gene.

In the Vinony graph

Within Vinony's link graph, CD151 is referenced by 501 other articles, and connects out to PubMed, Ensembl genome database project and CD1.

It sits within the topics Blood antigen systems, Clusters of differentiation and Genes on human chromosome 11.

Its subject is documented across 6 Wikipedia language editions.

Gene data

CD151

Name: CD151 molecule (Raph blood group)
Type: protein-coding
Position: 832,702–839,831 (+)
Aliases: EBS7, GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24
Ensembl: ENSG00000177697
RefSeq RNA: NM_001039490.2, NM_004357.5, NM_139029.2, NM_139030.4, XM_024448780.2
RefSeq protein: NP_001034579.1, NP_004348.2, NP_620598.1, NP_620599.1, XP_024304548.1

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008].