EPHA2

Also known as AW545284, Eck, Myk2, Sek-2, Sek2, ARCC2, CTPA

protein-coding gene in the species Homo sapiens

In the Vinony graph

Vinony's link graph records 132 inbound references to EPHA2, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.

It sits within the topics Genes on human chromosome 1, Long stubs with short prose and Tyrosine kinase receptors.

Vinony links it to 7 Wikipedia language editions.

Gene data

EPHA2

Name: EPH receptor A2
Type: protein-coding
Position: 16,124,337–16,156,141 (−)
Aliases: ARCC2, CTPA, CTPP1, CTRCT6, ECK
Ensembl: ENSG00000142627
RefSeq RNA: NM_001329090.2, NM_004431.5, XM_017000537.2, XM_047448259.1, XM_047448267.1
RefSeq protein: NP_001316019.1, NP_004422.2, XP_016856026.1, XP_047304215.1, XP_047304223.1

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010].