EPHA4

Also known as 2900005C20Rik, AI385584, Cek8, Hek8, Sek, Sek1, Tyro1

protein-coding gene in the species Homo sapiens

In the Vinony graph

Vinony's link graph records 122 inbound references to EPHA4, and connects out to PubMed, human chromosome 2 and protein tyrosine kinase.

Vinony files it under Genes on human chromosome 2 and Tyrosine kinase receptors.

Vinony links it to 6 Wikipedia language editions.

Gene data

EPHA4

Name: EPH receptor A4
Type: protein-coding
Position: 221,418,027–221,574,202 (−)
Aliases: EK8, HEK8, SEK, TYRO1
Ensembl: ENSG00000116106
RefSeq RNA: NM_001304536.2, NM_001304537.2, NM_001363748.2, NM_004438.5
RefSeq protein: NP_001291465.1, NP_001291466.1, NP_001350677.1, NP_004429.1

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015].