NFYC

Also known as CBF-C, CBFC, H1TF2A, HAP5, HSM, NF-YC, nuclear transcription factor Y subunit gamma

Nuclear transcription factor Y subunit gamma is a protein that in humans is encoded by the NFYC gene.

Gene data

NFYC

Name: nuclear transcription factor Y subunit gamma
Type: protein-coding
Position: 40,691,570–40,771,606 (+)
Aliases: CBF-C, CBFC, H1TF2A, HAP5, HSM, NF-YC
Ensembl: ENSG00000066136
RefSeq RNA: NM_001142587.2, NM_001142588.2, NM_001142589.2, NM_001142590.2, NM_001308114.1
RefSeq protein: NP_001136059.1, NP_001136060.1, NP_001136061.1, NP_001136062.1, NP_001295043.1

This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].