Structure via PubChem · Public domain (PubChem)
pramipexole
Sign in to saveAlso known as (-)-pramipexole, (S)-N 6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine, (S)-4,5,6,7-tetrahydro-N(6)-propyl-2,6-benzothiazolediamine
Pramipexole, sold under the brand Mirapex among others, is a medication used to treat Parkinson's disease and restless legs syndrome. In Parkinson's disease it may be used alone or together with levodopa. It is taken by mouth. Pramipexole is a dopamine agonist of the non-ergoline class.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 464213026
- Drug.image
- Pramipexole.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Pramipexole 3D-Structure Xtal.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Mirapex, Mirapexin, Sifrol, others
- Drug.MedlinePlus
- a697029
- Drug.DailyMedID
- Pramipexole
- Drug.pregnancy_AU
- B3
- Drug.routes_of_administration
- By mouth
- Drug.class
- Dopamine receptor agonist; Dopamine D2-like receptor agonist; Antiparkinsonian agent
- Drug.ATC_prefix
- N04
- Drug.ATC_suffix
- BC05
- Drug.legal_BR
- C1
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
via Wikipedia infobox
Chemical data
- Formula
- C10H17N3S
- Molecular weight
- 211.33 g/mol
- IUPAC name
- (6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
- SMILES
- CCCN[C@H]1CCC2=C(C1)SC(=N2)N
- InChIKey
- FASDKYOPVNHBLU-ZETCQYMHSA-N
- XLogP
- 1.9
- Polar surface area
- 79.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 211.114
Show 6 more facts
- chemical formula
- C₁₀H₁₇N₃S
- isomeric SMILES
- CCCN[C@H]1CCC2=C(C1)SC(=N2)N
- canonical SMILES
- CCCNC1CCC2=C(C1)SC(=N2)N
- World Health Organisation international non-proprietary name
- pramipexole
- defined daily dose
- 2.5
- Commons category
- Pramipexole
via Wikidata · CC0
~13 min read
Article
16 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Chemistry
- Synthesis
- Analogues
- Society and culture
- Brand names
- Research
- Further Parkinson's disease symptoms treatment
- Cerebral ischemia and reperfusion injury
- Traumatic brain injury
- Psychiatry
- Other indications
- Notes
- References
Pramipexole, sold under the brand Mirapex among others, is a medication used to treat Parkinson's disease and restless legs syndrome. In Parkinson's disease it may be used alone or together with levodopa. It is taken by mouth. Pramipexole is a dopamine agonist of the non-ergoline class.
Pramipexole was approved for medical use in the United States in 1997 and was first manufactured by Pharmacia and Upjohn. It is available as a generic medication. In 2023, it was the 201st most commonly prescribed medication in the United States, with more than 2million prescriptions.