SOX18
Sign in to saveAlso known as HLTS, HLTRS, SRY-box 18, SRY-box transcription factor 18
Transcription factor SOX-18 is a protein that in humans is encoded by the SOX18 gene.
Gene data
SOX18- Name
- SRY-box transcription factor 18
- Type
- protein-coding
- Position
- 64,047,582–64,049,639 (−)
- Aliases
- HLTRS, HLTS
- Ensembl
- ENSG00000203883
- RefSeq RNA
- NM_018419.3
- RefSeq protein
- NP_060889.1
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
SRY-box transcription factor 18
- Symbol
- SOX18
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:64,047,582-64,050,629
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 7546
- exact match
- identifiers.org/ncbigene/54345
- genomic end
- 64049639
- genomic start
- 62679076
- cytogenetic location
- 20q13.33
via Wikidata · CC0
~1 min read
Article
6 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
- External links
Transcription factor SOX-18 is a protein that in humans is encoded by the SOX18 gene.
== Function ==