SOX18

Also known as HLTS, HLTRS, SRY-box 18, SRY-box transcription factor 18

Transcription factor SOX-18 is a protein that in humans is encoded by the SOX18 gene.

In the Vinony graph

Vinony's link graph records 817 inbound references to SOX18, and connects out to PubMed, human chromosome 20 and homeobox.

It sits within the topics Genes on human chromosome 20 and Transcription factors.

Vinony links it to 6 Wikipedia language editions.

Gene data

SOX18

Name: SRY-box transcription factor 18
Type: protein-coding
Position: 64,047,582–64,050,629 (−)
Aliases: HLTRS, HLTS
Ensembl: ENSG00000203883
RefSeq RNA: NM_018419.3
RefSeq protein: NP_060889.1

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. [provided by RefSeq, Jul 2008].