Structure via PubChem · Public domain (PubChem)
تراپیدیل
Sign in to saveAlso known as AR-12008, Trapidil
Trapidil is used in the treatment of chronic stable angina pectoris. It is currently marketed in Japan under the brand name Rocornal.
In the Vinony graph
Vinony's link graph records 133 inbound references to تراپیدیل, and connects out to vasodilation, hirudin and coagulation factor X.
It sits within the topics Chemical pages without DrugBank identifier, Diethylamino compounds and Drugboxes which contain changes to verified fields.
Vinony links it to 6 Wikipedia language editions.
Chemical data
- Formula
- C10H15N5
- Molecular weight
- 205.26 g/mol
- IUPAC name
- N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
- SMILES
- CCN(CC)C1=CC(=NC2=NC=NN12)C
- InChIKey
- GSNOZLZNQMLSKJ-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 46.3 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
330 papers- Trapidil attenuates diabetic cardiomyopathy via GPX3/Nrf2-mediated inhibition of myocardial pyroptosis.Frontiers in pharmacology · 2025
- [Trapidil after one year].Minerva cardioangiologica · 1993
- Intrepide; Trapidil eluting stent.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2008
- Trapidil induces osteogenesis by upregulating the signaling of bone morphogenetic proteins.Cellular signalling · 2018
- Trapidil determines the fate of RHF rats through inhibition of ER stress.Archives of pharmacal research · 2020
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 205.132746
- Has use
- medication
Show 5 more facts
- chemical formula
- C₁₀H₁₅N₅
- canonical SMILES
- CCN(CC)C1=CC(=NC2=NC=NN12)C
- subject has role
- platelet aggregation inhibitors
- has characteristic
- bitterness
- Commons category
- Trapidil
Sources (2)
via Wikidata · CC0
Connections
vasodilation
Entity
hirudin
Entity
coagulation factor X
Protein
ximelagatran
Entity
medication
Entity
circulatory system
Entity
aspirin
Entity
digital object identifier
Entity
chemical formula
Entity
caffeine
Entity
nucleotide
Entity
sildenafil
Entity
citric acid
Entity
molar mass
Entity
cardiovascular disease
Entity
angina pectoris
Entity
PubMed
Entity
CAS Registry Number
Entity
diazepam
Entity
heparin
Entity