Also known as IGI, IGVPB, VPREB, CD179a, pre-B lymphocyte 1, V-set pre-B cell surrogate light chain 1
Immunoglobulin iota chain is a protein that in humans is encoded by the VPREB1 gene. VPREB1 has also recently been designated CD179A (cluster of differentiation 179A).
The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015].
via MyGene.info
Immunoglobulin iota chain is a protein that in humans is encoded by the VPREB1 gene. VPREB1 has also recently been designated CD179A (cluster of differentiation 179A).
== Function ==
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).