Also known as entrez:1633, deoxycytidine kinase
protein-coding gene in the species Homo sapiens
Gene data
DCK- Name
- deoxycytidine kinase
- Type
- protein-coding
- Position
- 70,992,538–71,030,914 (+)
- Ensembl
- ENSG00000156136
- RefSeq RNA
- NM_000788.3, XM_047449689.1, XM_054349068.1
- RefSeq protein
- NP_000779.1, XP_047305645.1, XP_054205043.1
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
deoxycytidine kinase
- Symbol
- DCK
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:70,992,538-71,030,914
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein DCK PDB 1p5z.png
Show 5 more facts
- HomoloGene ID
- 616
- genomic end
- 71896631
- exact match
- identifiers.org/ncbigene/1633
- genomic start
- 71858255
- cytogenetic location
- 4q13.3
via Wikidata · CC0
Connections
nucleotide
Entity
Q180686
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Ensembl genome database project
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nitrogen
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cancer
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phosphorus
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enzyme
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Wikidata
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alcohols
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gene
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chromosome
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digital object identifier
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chemotherapy
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carboxylic acid
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adenosine triphosphate
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phosphates
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DL-glutamic acid
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monomer
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bibcode
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human genome
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