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GeneQ18055578· pop 6· linked from 815 articles

Also known as BHLHC8, FIGALPHA, POF6, folliculogenesis specific bHLH transcription factor

Folliculogenesis-specific basic helix-loop-helix, also known as factor in the germline alpha (FIGalpha) or transcription factor FIGa, is a protein that in humans is encoded by the FIGLA gene. The FIGLA gene is a germ cell-specific transcription factor preferentially expressed in oocytes that can be found on human chromosome 2p13.3.

In the Vinony graph

Within Vinony's link graph, FIGLA is referenced by 815 other articles, and connects out to PubMed, human chromosome 2 and homeobox.

It sits within the topics Genes on human chromosome 2 and Transcription factors.

Its subject is documented across 6 Wikipedia language editions.

Gene data

FIGLA
Name
folliculogenesis specific bHLH transcription factor
Type
protein-coding
Aliases
BHLHC8, FIGALPHA, POF6

This gene encodes a protein that functions in postnatal oocyte-specific gene expression. The protein is a basic helix-loop-helix transcription factor that regulates multiple oocyte-specific genes, including genes involved in folliculogenesis and those that encode the zona pellucida. Mutations in this gene cause premature ovarian failure type 6. [provided by RefSeq, Sep 2009].

via MyGene.info

Gene · Ensembl

folliculogenesis specific bHLH transcription factor

Symbol
FIGLA
Biotype
Protein coding
Organism
Homo sapiens
Location
2:70,777,310-70,790,643
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
49294
found in taxon
Homo sapiens
genomic start
71004442
genomic end
71017775
cytogenetic location
2p13.3
Sources (4)

via Wikidata · CC0

~2 min read

Encyclopedic overview

4 sections
Contents
  • Function
  • Clinical significance
  • References
  • Further reading

Folliculogenesis-specific basic helix-loop-helix, also known as factor in the germline alpha (FIGalpha) or transcription factor FIGa, is a protein that in humans is encoded by the FIGLA gene. The FIGLA gene is a germ cell-specific transcription factor preferentially expressed in oocytes that can be found on human chromosome 2p13.3.

== Function ==

Excerpted from Wikipedia’s “FIGLA” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0

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