FIGLA
Sign in to saveAlso known as BHLHC8, FIGALPHA, POF6, folliculogenesis specific bHLH transcription factor
Folliculogenesis-specific basic helix-loop-helix, also known as factor in the germline alpha (FIGalpha) or transcription factor FIGa, is a protein that in humans is encoded by the FIGLA gene. The FIGLA gene is a germ cell-specific transcription factor preferentially expressed in oocytes that can be found on human chromosome 2p13.3.
Gene data
FIGLA- Name
- folliculogenesis specific bHLH transcription factor
- Type
- protein-coding
- Aliases
- BHLHC8, FIGALPHA, POF6
This gene encodes a protein that functions in postnatal oocyte-specific gene expression. The protein is a basic helix-loop-helix transcription factor that regulates multiple oocyte-specific genes, including genes involved in folliculogenesis and those that encode the zona pellucida. Mutations in this gene cause premature ovarian failure type 6. [provided by RefSeq, Sep 2009].
via MyGene.info
Gene · Ensembl
folliculogenesis specific bHLH transcription factor
- Symbol
- FIGLA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:70,777,310-70,790,643
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 49294
- exact match
- identifiers.org/ncbigene/344018
- genomic start
- 71004442
- genomic end
- 71017775
- cytogenetic location
- 2p13.3
Sources (4)
via Wikidata · CC0
~2 min read
Article
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Folliculogenesis-specific basic helix-loop-helix, also known as factor in the germline alpha (FIGalpha) or transcription factor FIGa, is a protein that in humans is encoded by the FIGLA gene. The FIGLA gene is a germ cell-specific transcription factor preferentially expressed in oocytes that can be found on human chromosome 2p13.3.
== Function ==