LTBP1

Name

latent transforming growth factor beta binding protein 1

Type

protein-coding

Position

32,946,472–33,400,509 (+)

Aliases

ARCL2E

Ensembl

ENSG00000049323

RefSeq RNA

NM_000627.4, NM_001166264.2, NM_001166265.2, NM_001166266.2, NM_001394905.1

RefSeq protein

NP_000618.4, NP_001159736.2, NP_001159737.2, NP_001159738.2, NP_001381834.1

The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

latent transforming growth factor beta binding protein 1

Symbol

LTBP1

Biotype

Protein coding

Organism

Homo sapiens

Location

2:32,946,472-33,400,509

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein LTBP1 PDB 1ksq.png

via Wikidata · CC0