MAP2K6

Also known as MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3, mitogen-activated protein kinase kinase 6

gene umano

In the Vinony graph

Vinony's link graph records 307 inbound references to MAP2K6, and connects out to mitogen-activated protein kinases, PubMed and human chromosome 17.

It is catalogued under topics including EC 2.7.12 and Genes on human chromosome 17.

Vinony links it to 4 Wikipedia language editions.

Gene data

MAP2K6

Name: mitogen-activated protein kinase kinase 6
Type: protein-coding
Position: 69,414,683–69,553,865 (+)
Aliases: CRCMSL, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3
Ensembl: ENSG00000108984
RefSeq RNA: NM_001330450.2, NM_002758.4, NM_031988.1, XM_005257516.3, XM_006721975.4
RefSeq protein: NP_001317379.1, NP_002749.2, XP_005257573.1, XP_006722038.1, XP_011523329.1

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008].