Also known as ARIX, CFEOM2, FEOM2, NCAM2, PMX2A, paired like homeobox 2a
Paired mesoderm homeobox protein 2A is a protein that in humans is encoded by the PHOX2A gene.
The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008].
via MyGene.info
Paired mesoderm homeobox protein 2A is a protein that in humans is encoded by the PHOX2A gene.
== Function ==
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).