MESP2

Also known as SCDO2, bHLHc6, mesoderm posterior bHLH transcription factor 2

Mesoderm posterior protein 2 (MESP2), also known as class C basic helix-loop-helix protein 6 (bHLHc6), is a protein that in humans is encoded by the MESP2 gene.

Gene data

MESP2

Name: mesoderm posterior bHLH transcription factor 2
Type: protein-coding
Aliases: SCDO2, bHLHc6

This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02). [provided by RefSeq, Oct 2008].

via MyGene.info

Gene · Ensembl

mesoderm posterior bHLH transcription factor 2

Symbol: MESP2
Biotype: Protein coding
Organism: Homo sapiens
Location: 15:89,760,591-89,778,754
Strand: Forward (+)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 7420
exact match: identifiers.org/ncbigene/145873
genomic end: 90321982
genomic start: 90303822
cytogenetic location: 15q26.1

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Contents

Function
Clinical significance
References
Further reading

Mesoderm posterior protein 2 (MESP2), also known as class C basic helix-loop-helix protein 6 (bHLHc6), is a protein that in humans is encoded by the MESP2 gene.

== Function ==