RFX2
Sign in to saveAlso known as regulatory factor X2
DNA-binding protein RFX2 is a protein that in humans is encoded by the RFX2 gene.
Gene data
RFX2- Name
- regulatory factor X2
- Type
- protein-coding
- Position
- 5,993,164–6,199,572 (−)
- Ensembl
- ENSG00000087903
- RefSeq RNA
- NM_000635.4, NM_134433.3, XM_017027107.2, XM_047439196.1, XM_047439197.1
- RefSeq protein
- NP_000626.2, NP_602309.1, XP_016882596.1, XP_047295152.1, XP_047295153.1
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
regulatory factor X2
- Symbol
- RFX2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:5,993,164-6,199,572
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 30980
- exact match
- identifiers.org/ncbigene/5990
- genomic end
- 6199583
- genomic start
- 5993175
- cytogenetic location
- 19p13.3
Sources (4)
via Wikidata · CC0
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- Further reading
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DNA-binding protein RFX2 is a protein that in humans is encoded by the RFX2 gene.
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites.