Structure via PubChem · Public domain (PubChem)
tropatepine
Sign in to saveTropatepine (brand name Lepticur) is an anticholinergic used as an antiparkinsonian agent.
In the Vinony graph
Within Vinony's link graph, tropatepine is referenced by 561 other articles, and connects out to atropine, muscarinic acetylcholine receptor family and eslicarbazepine acetate.
It is catalogued under topics including Chemical pages without DrugBank identifier, Dibenzothiepines and Drugs with no legal status.
Its subject is documented across 6 Wikipedia language editions.
Chemical data
- Formula
- C22H23NS
- Molecular weight
- 333.5 g/mol
- IUPAC name
- 3-(6H-benzo[c][1]benzothiepin-11-ylidene)-8-methyl-8-azabicyclo[3.2.1]octane
- SMILES
- CN1C2CCC1CC(=C3C4=CC=CC=C4CSC5=CC=CC=C53)C2
- InChIKey
- JOQKFRLFXDPXHX-UHFFFAOYSA-N
- XLogP
- 4.8
- Polar surface area
- 28.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 333.155121
Show 2 more facts
- chemical formula
- C₂₂H₂₃NS
- canonical SMILES
- CN1C2CCC1CC(=C3C4=CC=CC=C4CSC5=CC=CC=C53)C2
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Tropatepine (brand name Lepticur) is an anticholinergic used as an antiparkinsonian agent.
==Synthesis== Tropatepine can be synthesized from 3-chlorotropane (1). A Grignard reaction between 3-chlorotropane and dibenzo[b,e]thiepin-11(6H)-one (2) followed by dehydration to the olefin produces tropatepine (3). thumb|center|300px|Synthesis of tropatepine
Excerpted from Wikipedia’s “tropatepine” article, available under the CC BY-SA 4.0 licence.