JUNB
Sign in to saveAlso known as AP-1, JunB proto-oncogene, AP-1 transcription factor subunit
Transcription factor jun-B is a protein that, in humans, is encoded by the JUNB gene. Transcription factor jun-B is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.
Gene data
JUNB- Name
- JunB proto-oncogene, AP-1 transcription factor subunit
- Type
- protein-coding
- Aliases
- AP-1
Enables sequence-specific double-stranded DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of transcription factor AP-1 complex. Biomarker of Hodgkin's lymphoma and anaplastic large cell lymphoma. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Gene · Ensembl
JunB proto-oncogene, AP-1 transcription factor subunit
- Symbol
- JUNB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:12,791,486-12,793,315
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 7390
- exact match
- identifiers.org/ncbigene/3726
- genomic end
- 12904124
- genomic start
- 12791486
- cytogenetic location
- 19p13.13
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Interactions
- See also
- References
- Further reading
- External links
Transcription factor jun-B is a protein that, in humans, is encoded by the JUNB gene. Transcription factor jun-B is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.
==Interactions== JUNB has been shown to interact with BRCA1, and SMAD3.