Also known as AP-1, JunB proto-oncogene, AP-1 transcription factor subunit
Transcription factor jun-B is a protein that, in humans, is encoded by the JUNB gene. Transcription factor jun-B is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.
Enables sequence-specific double-stranded DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of transcription factor AP-1 complex. Biomarker of Hodgkin's lymphoma and anaplastic large cell lymphoma. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Transcription factor jun-B is a protein that, in humans, is encoded by the JUNB gene. Transcription factor jun-B is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.
==Interactions== JUNB has been shown to interact with BRCA1, and SMAD3.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).