CD24 molecule

Also known as CD24 antigen (small cell lung carcinoma cluster 4 antigen), Small cell lung carcinoma cluster 4 antigen, signal transducer CD24, CD24

Signal transducer CD24 also known as cluster of differentiation 24 or heat stable antigen CD24 (HSA) is a protein that in humans is encoded by the CD24 gene. CD24 is a cell adhesion molecule.

Protein · UniProt

Signal transducer CD24

Gene: CD24
Organism: Homo sapiens (Human)
Length: 80 aa
Molecular mass: 8,083 Da
Evidence: 1: Evidence at protein level

May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells (PubMed:11313396). In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and H…

Alternative splicingCell membraneGlycoproteinGPI-anchorLipoproteinMembraneProteomics identificationReference proteome

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Swiss-Prot (reviewed) · via UniProt

Research

690 papers

CD24 for Cardiovascular Researchers: A Key Molecule in Cardiac Immunology, Marker of Stem Cells and Target for Drug Development.Journal of personalized medicine · 2021
Tumour biological aspects of CD24, a mucin-like adhesion molecule.Journal of molecular histology · 2004
Targeting macrophages in hematological malignancies: recent advances and future directions.Journal of hematology & oncology · 2022
Extracellular vesicles and the lung: from disease pathogenesis to biomarkers and treatments.Physiological reviews · 2025
Radiotherapy in combination with CD47 blockade elicits a macrophage-mediated abscopal effect.Nature cancer · 2022

via PubMed

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Article

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Contents

Function
References
Further reading
External links

Signal transducer CD24 also known as cluster of differentiation 24 or heat stable antigen CD24 (HSA) is a protein that in humans is encoded by the CD24 gene. CD24 is a cell adhesion molecule.

== Function ==